Prescription Medicine for Heartburn and GERD: Varieties and Manufacturers


Frequent heartburn or gastroesophageal reflux illness (GERD) that happens greater than twice per week normally responds greatest to heartburn medication that you simply take each day moderately than simply once you really feel the heartburn. A lot of the over-the-counter remedies should not meant to be taken each day for a very long time. Examine in together with your physician to see when you want a prescription medication on your heartburn.

Histamine-2 (H2) Blockers for Heartburn and Reflux

In prescription kind (normally increased doses than the over-the-counter variations), H2 blockers can usually relieve heartburn and deal with reflux, particularly when you’ve by no means had therapy earlier than. These medication are notably helpful at assuaging heartburn, however is probably not nearly as good for treating esophagitis (irritation that happens within the esophagus) that’s the results of GERD.

Histamine stimulates acid manufacturing, particularly after meals, so H2 blockers are greatest taken half-hour earlier than meals. They can be taken at bedtime to suppress nighttime manufacturing of acid. Examples of prescription H2 blockers:

Unwanted effects can embody headache, belly ache, diarrhea, nausea, gasoline, sore throat, runny nostril, and dizziness. 

Be aware that the H2 blocker ranitidine was faraway from the market in 2020 as a result of it was discovered to include carcinogens.

Proton Pump Inhibitors (PPIs) for Heartburn and Reflux

Relying on the supply of your heartburn or reflux, your physician can prescribe medication that block acid manufacturing extra successfully and for an extended time period than the H2 blockers, particularly the household of medicines docs name proton pump inhibitors. PPIs are greatest taken an hour earlier than meals. They embody:

Most docs don’t consider that one drug is considerably more practical than the others in managing GERD. These medicines are additionally good for safeguarding the esophagus from acid in order that esophageal irritation can heal.

Unwanted effects can embody headache, diarrhea, belly ache, bloating, constipation, nausea, and gasoline.

Promotility Brokers for Heartburn and Reflux

Promotility brokers work by stimulating the muscle mass of the gastrointestinal tract, which can assist forestall acids from staying within the abdomen too lengthy, and strengthening the decrease esophageal sphincter, decreasing reflux into the esophagus. Metoclopramide (Reglan) is a promotility agent often used to deal with heartburn related to GERD. The unwanted side effects of Reglan could be severe and should embody drowsiness, fatigue, diarrhea, restlessness, and motion issues.

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