Overview, Makes use of, Aspect Results, Precautions, Interactions, Dosing and Evaluations

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Ames, F. R. and Cridland, S. Anticonvulsant impact of cannabidiol. S.Afr.Med.J. 1-4-1986;69(1):14. View summary.

Barnes, M. P. Sativex: scientific efficacy and tolerability within the therapy of signs of a number of sclerosis and neuropathic ache. Knowledgeable.Opin.Pharmacother. 2006;7(5):607-615. View summary.

Carlini, E. A. and Cunha, J. M. Hypnotic and antiepileptic results of cannabidiol. J Clin Pharmacol 1981;21(8-9 Suppl):417S-427S. View summary.

Collin, C., Davies, P., Mutiboko, I. Ok., and Ratcliffe, S. Randomized managed trial of cannabis-based drugs in spasticity brought on by a number of sclerosis. Eur.J.Neurol. 2007;14(3):290-296. View summary.

Collin, C., Ehler, E., Waberzinek, G., Alsindi, Z., Davies, P., Powell, Ok., Notcutt, W., O’Leary, C., Ratcliffe, S., Novakova, I., Zapletalova, O., Pikova, J., and Ambler, Z. A double-blind, randomized, placebo-controlled, parallel-group research of Sativex, in topics with signs of spasticity as a result of a number of sclerosis. Neurol.Res. 2010;32(5):451-459. View summary.

Consroe, P., Kennedy, Ok., and Schram, Ok. Assay of plasma cannabidiol by capillary gasoline chromatography/ion lure mass spectroscopy following high-dose repeated every day oral administration in people. Pharmacol Biochem.Behav. 1991;40(3):517-522. View summary.

Consroe, P., Laguna, J., Allender, J., Snider, S., Stern, L., Sandyk, R., Kennedy, Ok., and Schram, Ok. Managed scientific trial of cannabidiol in Huntington’s illness. Pharmacol Biochem.Behav. 1991;40(3):701-708. View summary.

Cunha, J. M., Carlini, E. A., Pereira, A. E., Ramos, O. L., Pimentel, C., Gagliardi, R., Sanvito, W. L., Lander, N., and Mechoulam, R. Persistent administration of cannabidiol to wholesome volunteers and epileptic sufferers. Pharmacology 1980;21(3):175-185. View summary.

Harvey, D. J., Samara, E., and Mechoulam, R. Comparative metabolism of cannabidiol in canine, rat and man. Pharmacol Biochem.Behav. 1991;40(3):523-532. View summary.

Iuvone, T., Esposito, G., Esposito, R., Santamaria, R., Di Rosa, M., and Izzo, A. A. Neuroprotective impact of cannabidiol, a non-psychoactive part from Hashish sativa, on beta-amyloid-induced toxicity in PC12 cells. J Neurochem. 2004;89(1):134-141. View summary.

Ohlsson, A., Lindgren, J. E., Andersson, S., Agurell, S., Gillespie, H., and Hollister, L. E. Single-dose kinetics of deuterium-labelled cannabidiol in man after smoking and intravenous administration. Biomed.Environ Mass Spectrom. 1986;13(2):77-83. View summary.

Srivastava, M. D., Srivastava, B. I., and Brouhard, B. Delta9 tetrahydrocannabinol and cannabidiol alter cytokine manufacturing by human immune cells. Immunopharmacology 1998;40(3):179-185. View summary.

Trembly B, Sherman M. Double-blind scientific research of cannabidiol as a secondary anticonvulsant. Marijuana ’90 Worldwide Convention on Hashish and Cannabinoids 1990;2:5.

Wade, D. T., Collin, C., Stott, C., and Duncombe, P. Meta-analysis of the efficacy and security of Sativex (nabiximols), on spasticity in folks with a number of sclerosis. Mult.Scler. 2010;16(6):707-714. View summary.

Wade, D. T., Makela, P., Robson, P., Home, H., and Bateman, C. Do cannabis-based medicinal extracts have basic or particular results on signs in a number of sclerosis? A double-blind, randomized, placebo-controlled research on 160 sufferers. Mult.Scler. 2004;10(4):434-441. View summary.

Wade, D. T., Robson, P., Home, H., Makela, P., and Aram, J. A preliminary managed research to find out whether or not whole-plant hashish extracts can enhance intractable neurogenic signs. Clin.Rehabil. 2003;17(1):21-29. View summary.

Watzl, B., Scuderi, P., and Watson, R. R. Marijuana parts stimulate human peripheral blood mononuclear cell secretion of interferon-gamma and suppress interleukin-1 alpha in vitro. Int J Immunopharmacol. 1991;13(8):1091-1097. View summary.

Aviello G, Romano B, Borrelli F, et al. Chemopreventive impact of the non-psychotropic phytocannabinoid cannabidiol on experimental colon most cancers. J Mol Med (Berl) 2012;90(8):925-34. View summary.

Bergamaschi MM, Queiroz RH, Chagas MH, et al. Cannabidiol reduces the nervousness induced by simulated public talking in treatment-naïve social phobia sufferers. Neuropsychopharmacology 2011;36(6):1219-26. View summary.

Bisogno T, Di Marzo Y. The position of the endocannabinoid system in Alzheimer’s illness: info and hypotheses. Curr Pharm Des 2008;14(23):2299-3305. View summary.

Booz GW. Cannabidiol as an emergent therapeutic technique for lessening the impression of irritation on oxidative stress. Free Radic Biol Med 2011;51(5):1054-61. View summary.

Bornheim LM, Everhart ET, Li J, Correia MA. Characterization of cannabidiol-mediated cytochrome P450 inactivation. Biochem Pharmacol 1993;45(6):1323-31. View summary.

Brady CM, DasGupta R, Dalton C, et al. An open-label research of cannabis-based extracts for bladder dysfuntion in superior a number of sclerosis. Mult Scler 2004;10(4):425-33. View summary.

Campos AC, Moreira FA, Gomes FV, et al. A number of mechanisms concerned within the large-spectrum therapeutic potential of cannabidiol in psychiatric issues. Philos Trans R Soc Lond B Biol Sci 2012;367(1607):3364-78. View summary.

Cannabidiol Now Exhibiting Up In Dietary Dietary supplements. Pure Medicines Web page. Obtainable at: Accessed: Could 31, 2015.

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Consroe P, Sandyk R, Snider SR. Open label analysis of cannabidiol in dystonic motion issues. Int J Neurosci 1986;30(4):277-82. View summary.

Crippa JA, Derenusson GN, Ferrari TB, et al. Neural foundation of anxiolytic results of cannabidiol (CBD) in generalized social nervousness dysfunction: a preliminary report. J Psychopharmacol 2011;25(1):121-30. View summary.

Dalterio S, Steger R, Mayfield D, Bartke A. Early cannabinoid publicity influences neuroendocrine and reproductive features in mice: II. Postnatal results. Pharmacol Biochem Behav 1984;20(1):115-23. View summary.

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Englund A, Morrison PD, Nottage J, et al. Cannabidiol inhibits THC-elicited paranoid signs and hippocampal-dependent reminiscence impairment. J Psychopharmacol 2013;27(1):19-27. View summary.

Esposito G, De Filippis D, Maiuri MC, et al. Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide manufacturing in beta-amyloid stimulated PC12 neurons by means of p38 MAP kinase and NF-kappaB involvement. Neurosci Lett 2006;399(1-2):91-5. View summary.

Esposito G, Scuderi C, Savani C, et al. Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression. Br J Pharmacol 2007;151(8):1272-9. View summary.

FDA and Marijuana: Questions and Solutions. U.S. Meals and Drug Administration Web page. Obtainable at: Accessed: Could 31, 2015.

Formukong EA, Evans AT, Evans FJ. Analgesic and anti inflammatory exercise of constituents of Hashish sativa L. Irritation 1988;12(4):361-71. View summary.

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Guimaraes VM, Zuardi AW, Del Bel EA, Guimaraes FS. Cannabidiol will increase Fos expression within the nucleus accumbens however not within the dorsal striatum. Life Sci 2004;75(5):633-8. View summary.

Harvey DJ. Absorption, distribution, and biotransformation of the cannabinoids. Marijuana and Drugs. 1999;91-103.

Historical past. GW Prescribed drugs Web page. Obtainable at: Accessed: Could 27, 2015.

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Lee CY, Wey SP, Liao MH, et al. A comparative research on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells. Int Immunopharmacol 2008;8(5):732-40. View summary.

Leighty EG, Fentiman AF Jr, Foltz RL. Lengthy-retained metabolites of delta9- and delta8-tetrahydrocannabinols recognized as novel fatty acid conjugates. Res Commun Chem Pathol Pharmacol 1976;14(1):13-28. View summary.

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Magen I, Avraham Y, Ackerman Z, et al. Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation. J Hepatol 2009;51(3):528-34. View summary.

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Massi P, Solinas M, Cinquina V, Parolaro D. Cannabidiol as a possible anticancer drug. Br J Clin Pharmacol 2013;75(2):303-12. View summary.

Matsuyama SS, Fu TK. In vivo cytogenetic results of cannabinoids. J Clin Psychopharmacol 1981;1(3):135-40. View summary.

Mechoulam R, Parker LA, Gallily R. Cannabidiol: an summary of some pharmacological facets. J Clin Pharmacol 2002;42(11 Suppl):11S-19S. View summary.

Monti JM. Hypnoticlike results of cannabidiol within the rat. Psychopharmacology (Berl) 1977;55(3):263-5. View summary.

Moreira FA, Guimaraes FS. Cannabidiol inhibits the hyperlocomotion induced by psychomimetic medication in mice. Eur J Pharmacol 2005;512(2-3):199-205. View summary.

Morgan CJ, Das RK, Joye A, et al. Cannabidiol reduces cigarette consumption in tobacco people who smoke: preliminary findings. Addict Behav 2013;38(9):2433-6. View summary.

Murillo-Rodriguez E, Millan-Aldaco D, Palomero-Rivero M, et al. Cannabidiol, a constituent of Hashish sativa, modulates sleep in rats. FEBS Lett 2006;580(18):4337-45. View summary.

Notcutt W, Langford R, Davies P, et al. A placebo-controlled, parallel group, randomized withdrawal research of topics with signs of spasticity as a result of a number of sclerosis who’re receiving long-term Sativex (nabiximols). Mult Scler 2012;18(2):219-28. View summary.

Novotna A, Mares J, Ratcliffe S, et al. A randomized, double-blind, placebo-controlled, parallel-group, enriched-design research of nabiximols* (Sativex), as add-on remedy, in topics with refractory spasticity trigger by a number of sclerosis. Eur J Neurol 2011;18(9):1122-31. View summary.

Overview. GW Prescribed drugs Web page. Obtainable at: Accessed: Could 31, 2015.

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Pickens JT. Sedative exercise of hashish in relation to its delta’-trans-tetrahydrocannabinol and cannabidiol content material. Br J Pharmacol 1981;72(4):649-56. View summary.

Rosenkrantz H, Fleischman RW, Grant RJ. Toxicity of short-term administration of cannabinoids to rhesus monkeys. Toxicol Appl Pharmacol 1981;58(1):118-31. View summary.

Samara E, Bialer M, Mechoulam R. Pharmacokinetics of cannabidiol in canines. Drug Metab Dispos 1988;16(3):469-72. View summary.

Sativex oromucosal spray. Abstract of product traits. GW Pharma, Ltd. Obtainable at: Up to date: Could 2015. Accessed: Could 31, 2015.

Schubart CD, Sommer IE, Fusar-Poli P, et al. Cannabidiol as a possible therapy for psychosis. Eur Neuropsychopharmacol 2014;24(1):51-64. View summary.

Schubart CD, Sommer IE, van Gastel WA, et al. Hashish with excessive cannabidiol content material is related to fewer psychotic experiences. Schizophr Res 2011;130(1-3):216-21. View summary.

Serpell MG, Notcutt W, Collin C. Sativex long-term use: an open-label trial in sufferers with spasticity as a result of a number of sclerosis. J Neurol 2013;260(1):285-95. View summary.

Shrivastava A, Kuzontkoski PM, Groopman JE, Prasad A. Cannabidiol induces programmed cell dying in breast most cancers cells by coordinating the cross-talk between apoptosis and autophagy. Mol Most cancers Ther 2011;10(7):1161-72. View summary.

Toth CC, Jedrzejewski NM, Ellis CL, Frey WH. Cannabinoid-mediated modulation of neuropathic ache and microglial accumulation in a mannequin of murine sort 1 diabetic peripheral neuropathic ache. Mol Ache 2010;6:16. View summary.

Valvassori SS, Elias G, de Souza B, et al. Results of cannabidiol on amphetamine-induced oxidative stress era in an animal mannequin of mania. J Psychopharmacol 2011;25(2):274-80. View summary.

Wade DT, Makela PM, Home H, et al. Lengthy-term use of a cannabis-based therapy in spasticity and different signs in a number of sclerosis. Mult Scler 2006;12(5):639-45. View summary.

Yadav V, Bever C Jr, Bowen J, et al. Abstract of evidence-based guideline: complementary and various drugs in a number of sclerosis: report of the rule of thumb growth subcommittee of the American Academy of Neurology. Neurology. 2014;82(12):1083-92. View summary.

Yamaori S, Ebisawa J, Okushima Y, et al. Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: position of phenolic hydroxyl teams within the resorcinol moiety. Life Sci 2011;88(15-16):730-6. View summary.

Yamaori S, Kushihara M, Yamamoto I, Watanabe Ok. Characterization of main phytocannabinoids, cannabidiol and cannabinol, as isoform-selective potent inhibitors of human CYP1 enzymes. Biochem Pharmacol 2010;79(11):1691-8. View summary.

Yamaori S, Maeda C, Yamamoto I, Watanabe Ok. Differential inhibition of human cytochrome P450 2A6 and 2B6 by main phytocannabinoids. Forensic Toxicol 2011;29:117-24.

Yamaori S, Okamoto Y, Yamamoto I, Watanabe Ok. Cannabidiol, a significant phytocannabinoid, as a potent atypical inhibitor for CYP2D6. Drug Metab Dispos 2011;39(11):2049-56. View summary.

Zuardi A, Crippa J, Dursun S, et al. Cannabidiol was ineffective for manic episode of bipolar affective dysfunction. J Psychopharmacol 2010;24(1):135-7. View summary.

Zuardi AW, Cosme RA, Graeff FG, Guimaraes FS. Results of ipsapirone and cannabidiol on human experimental nervousness. J Psychopharmacol 1993;7(1 Suppl):82-8. View summary.

Zuardi AW, Crippa JA, Hallak JE, et al. Cannabidiol for the therapy of psychosis in Parkinson’s illness. J Psychopharmacol 2009;23(8):979-83. View summary.

Zuardi AW, Crippa JA, Hallak JE, et al. Cannabidiol, a Hashish sativa constituent, as an antipsychotic drug. Braz J Med Biol Res 2006;39(4):421-9. View summary.

Zuardi AW, Morais SL, Guimaraes FS, Mechoulam R. Antipsychotic impact of cannabidiol. J Clin Psychiatry 1995;56(10):485-6. View summary.

Zuardi AW. Cannabidiol: from an inactive cannabinoid to a drug with broad spectrum of motion. Rev Bras Psiquiatr 2008;30(3):271-80. View summary.

Ames, F. R. and Cridland, S. Anticonvulsant impact of cannabidiol. S.Afr.Med.J. 1-4-1986;69(1):14. View summary.

Barnes, M. P. Sativex: scientific efficacy and tolerability within the therapy of signs of a number of sclerosis and neuropathic ache. Knowledgeable.Opin.Pharmacother. 2006;7(5):607-615. View summary.

Collin, C., Davies, P., Mutiboko, I. Ok., and Ratcliffe, S. Randomized managed trial of cannabis-based drugs in spasticity brought on by a number of sclerosis. Eur.J.Neurol. 2007;14(3):290-296. View summary.

Collin, C., Ehler, E., Waberzinek, G., Alsindi, Z., Davies, P., Powell, Ok., Notcutt, W., O’Leary, C., Ratcliffe, S., Novakova, I., Zapletalova, O., Pikova, J., and Ambler, Z. A double-blind, randomized, placebo-controlled, parallel-group research of Sativex, in topics with signs of spasticity as a result of a number of sclerosis. Neurol.Res. 2010;32(5):451-459. View summary.

Consroe, P., Kennedy, Ok., and Schram, Ok. Assay of plasma cannabidiol by capillary gasoline chromatography/ion lure mass spectroscopy following high-dose repeated every day oral administration in people. Pharmacol Biochem.Behav. 1991;40(3):517-522. View summary.

Consroe, P., Laguna, J., Allender, J., Snider, S., Stern, L., Sandyk, R., Kennedy, Ok., and Schram, Ok. Managed scientific trial of cannabidiol in Huntington’s illness. Pharmacol Biochem.Behav. 1991;40(3):701-708. View summary.

Crippa, J. A., Zuardi, A. W., Garrido, G. E., Wichert-Ana, L., Guarnieri, R., Ferrari, L., Azevedo-Marques, P. M., Hallak, J. E., McGuire, P. Ok., and Filho, Busatto G. Results of cannabidiol (CBD) on regional cerebral blood stream. Neuropsychopharmacology 2004;29(2):417-426. View summary.

Crippa, J. A., Zuardi, A. W., Martin-Santos, R., Bhattacharyya, S., Atakan, Z., McGuire, P., and Fusar-Poli, P. Hashish and nervousness: a crucial assessment of the proof. Hum.Psychopharmacol. 2009;24(7):515-523. View summary.

Cunha, J. M., Carlini, E. A., Pereira, A. E., Ramos, O. L., Pimentel, C., Gagliardi, R., Sanvito, W. L., Lander, N., and Mechoulam, R. Persistent administration of cannabidiol to wholesome volunteers and epileptic sufferers. Pharmacology 1980;21(3):175-185. View summary.

Harvey, D. J., Samara, E., and Mechoulam, R. Comparative metabolism of cannabidiol in canine, rat and man. Pharmacol Biochem.Behav. 1991;40(3):523-532. View summary.

Iuvone, T., Esposito, G., Esposito, R., Santamaria, R., Di Rosa, M., and Izzo, A. A. Neuroprotective impact of cannabidiol, a non-psychoactive part from Hashish sativa, on beta-amyloid-induced toxicity in PC12 cells. J Neurochem. 2004;89(1):134-141. View summary.

Massi, P., Vaccani, A., Bianchessi, S., Costa, B., Macchi, P., and Parolaro, D. The non-psychoactive cannabidiol triggers caspase activation and oxidative stress in human glioma cells. Cell Mol.Life Sci. 2006;63(17):2057-2066. View summary.

Massi, P., Vaccani, A., Ceruti, S., Colombo, A., Abbracchio, M. P., and Parolaro, D. Antitumor results of cannabidiol, a nonpsychoactive cannabinoid, on human glioma cell strains. J Pharmacol Exp.Ther. 2004;308(3):838-845. View summary.

Ohlsson, A., Lindgren, J. E., Andersson, S., Agurell, S., Gillespie, H., and Hollister, L. E. Single-dose kinetics of deuterium-labelled cannabidiol in man after smoking and intravenous administration. Biomed.Environ Mass Spectrom. 1986;13(2):77-83. View summary.

Srivastava, M. D., Srivastava, B. I., and Brouhard, B. Delta9 tetrahydrocannabinol and cannabidiol alter cytokine manufacturing by human immune cells. Immunopharmacology 1998;40(3):179-185. View summary.

Trembly B, Sherman M. Double-blind scientific research of cannabidiol as a secondary anticonvulsant. Marijuana ’90 Worldwide Convention on Hashish and Cannabinoids 1990;2:5.

Wade, D. T., Collin, C., Stott, C., and Duncombe, P. Meta-analysis of the efficacy and security of Sativex (nabiximols), on spasticity in folks with a number of sclerosis. Mult.Scler. 2010;16(6):707-714. View summary.

Wade, D. T., Makela, P., Robson, P., Home, H., and Bateman, C. Do cannabis-based medicinal extracts have basic or particular results on signs in a number of sclerosis? A double-blind, randomized, placebo-controlled research on 160 sufferers. Mult.Scler. 2004;10(4):434-441. View summary.

Wade, D. T., Robson, P., Home, H., Makela, P., and Aram, J. A preliminary managed research to find out whether or not whole-plant hashish extracts can enhance intractable neurogenic signs. Clin.Rehabil. 2003;17(1):21-29. View summary.

Watzl, B., Scuderi, P., and Watson, R. R. Marijuana parts stimulate human peripheral blood mononuclear cell secretion of interferon-gamma and suppress interleukin-1 alpha in vitro. Int J Immunopharmacol. 1991;13(8):1091-1097. View summary.

Weiss, L., Zeira, M., Reich, S., Har-Noy, M., Mechoulam, R., Slavin, S., and Gallily, R. Cannabidiol lowers incidence of diabetes in non-obese diabetic mice. Autoimmunity 2006;39(2):143-151. View summary.

Zuardi, A. W., Shirakawa, I., Finkelfarb, E., and Karniol, I. G. Motion of cannabidiol on the nervousness and different results produced by delta 9-THC in regular topics. Psychopharmacology (Berl) 1982;76(3):245-250. View summary.

“GW Prescribed drugs plc and Its U.S. Subsidiary Greenwich Biosciences, Inc. Announce That
EPIDIOLEX® (cannabidiol) Oral Answer Has Been Descheduled And Is No Longer A Managed
Substance.” GW Prescribed drugs, 6 April 2020. Press launch.

97021 Jadoon KA, Ratcliffe SH, Barrett DA, et al. Efficacy and security of cannabidiol and tetrahydrocannabivarin on glycemic and lipid parameters in sufferers with sort 2 diabetes: a randomized, double-blind, placebo-controlled, parallel group pilot research. Diabetes Care. 2016 Oct;39(10):1777-86. View summary.

Agriculture Enchancment Act, S. 10113, one hundred and fifteenth Cong. (2018) or S. 12619, one hundred and fifteenth Cong. (2018).

Anderson LL, Absalom NL, Abelev SV, et al. Coadministered cannabidiol and clobazam: Preclinical proof for each pharmacodynamic and pharmacokinetic interactions. Epilepsia. 2019. View summary.

Anderson LL, Doohan PT, Oldfield L, et al. Citalopram and Cannabidiol: In Vitro and In Vivo Proof of Pharmacokinetic Interactions Related to the Remedy of Nervousness Problems in Younger Folks. J Clin Psychopharmacol. 2021. View summary.

Appiah-Kusi E, Petros N, Wilson R, et al. Results of short-term cannabidiol therapy on response to social stress in topics at scientific excessive danger of creating psychosis.
Psychopharmacology (Berl). 2020 Jan 8.
View summary.

Arkell TR, Lintzeris N, Kevin RC, et al. Cannabidiol (CBD) content material in vaporized hashish doesn’t stop tetrahydrocannabinol (THC)-induced impairment of driving and cognition. Psychopharmacology (Berl). 2019;236(9):2713-2724. View summary.

Arkell TR, Vinckenbosch F, Kevin RC, Theunissen EL, McGregor IS, Ramaekers JG. Impact of Cannabidiol and ?9-Tetrahydrocannabinol on Driving Efficiency: A Randomized Scientific Trial. JAMA. 2020;324(21):2177-2186. View summary.

Arout CA, Haney M, Herrmann ES, Bedi G, Cooper ZD. The dose-dependent analgesic results, abuse legal responsibility, security and tolerability of oral cannabidiol in wholesome people. Br J Clin Pharmacol. 2021. View summary.

Aviello G, Romano B, Borrelli F, et al. Chemopreventive impact of the non-psychotropic phytocannabinoid cannabidiol on experimental colon most cancers. J Mol Med (Berl) 2012;90(8):925-34. View summary.

Baranowska-Kuczko M, Kozlowska H, Kloza M, et al. Vasoprotective Endothelial Results of Persistent Cannabidiol Remedy and Its Affect on the Endocannabinoid System in Rats with Main and Secondary Hypertension. Prescribed drugs (Basel) 2021;14(11):1120. View summary.

Bass J, Linz DR. A Case of Toxicity from Cannabidiol Gummy Ingestion. Cureus. 2020;12(4):e7688. View summary.

Bebee B, Taylor DM, Bourke E, et al. The CANBACK trial: a randomised, managed scientific trial of oral cannabidiol for folks presenting to the emergency division with acute low again ache. Med J Aust. 2021;214(8):370-375. View summary.

Ben-Menachem E, Gunning B, Arenas Cabrera CM, et al. A Part II Randomized Trial to Discover the Potential for Pharmacokinetic Drug-Drug Interactions with Stiripentol or Valproate when Mixed with Cannabidiol in Sufferers with Epilepsy. CNS Medicine. 2020;34(6):661-672. View summary.

Bergamaschi MM, Queiroz RH, Chagas MH, et al. Cannabidiol reduces the nervousness induced by simulated public talking in treatment-naïve social phobia sufferers. Neuropsychopharmacology 2011;36(6):1219-26. View summary.

Berger BA, Stolz U, Colvin J, Otten EJ. Epidemiology of cannabidiol associated instances reported within the Nationwide Poison Knowledge System – 2019-2020. Am J Emerg Med. 2021;48:218-223. View summary.

Bergeria CL, Spindle TR, Cone EJ, et al. Pharmacokinetic Profile of ?9-tetrahydrocannabinol, Cannabidiol and Metabolites in Blood following Vaporization and Oral Ingestion of Cannabidiol Merchandise. J Anal Toxicol 2022. View summary.

Birnbaum AK, Karanam A, Marino SE, et al. Meals impact on pharmacokinetics of cannabidiol oral capsules in grownup sufferers with refractory epilepsy. Epilepsia. 2019 Aug;60(8):1586-1592. View summary.

Bisogno T, Di Marzo Y. The position of the endocannabinoid system in Alzheimer’s illness: info and hypotheses. Curr Pharm Des 2008;14(23):2299-3305. View summary.

Bloomfield MAP, Inexperienced SF, Hindocha C, et al. The consequences of acute cannabidiol on cerebral blood stream and its relationship to reminiscence: An arterial spin labelling magnetic resonance imaging research. J Psychopharmacol. 2020;34(9):981-989. View summary.

Bloomfield MAP, Yamamori Y, Hindocha C, et al. The acute results of cannabidiol on emotional processing and nervousness: a neurocognitive imaging research. Psychopharmacology (Berl) 2022. View summary.

Bolsoni LM, Crippa JAS, Hallak JEC, Guimarães FS, Zuardi AW. Results of cannabidiol on signs induced by the recall of traumatic occasions in sufferers with posttraumatic stress dysfunction. Psychopharmacology (Berl) 2022. View summary.

Bonn-Miller MO, Loflin MJE, Thomas BF, Marcu JP, Hyke T, Vandrey R. Labeling accuracy of cannabidiol extracts bought on-line. JAMA 2017 Nov;318(17):1708-9. View summary.

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